International conference “ADVANCES IN TRANSLATIONAL MEDICINE”

7-9 November 2024, Grand Hotel Sofia, Sofia, Bulgaria

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PROGRAM

EATRIS-Bulgaria Annual Conference 2024

7 November 2024, Grand Hotel Sofia, Sofia, Bulgaria

15.00 – 16.00 Registration Grand Hotel Sofia “Sofia” Hall

16.00 – 16.30 Opening and welcome addresses

            Honorary Chairmen (Atanas Atanassov, Roumen Pankov)

            Science Directorate, Ministry of Education and Science (Milena Glavcheva)

            Dean of Faculty of Biology (Tanya Topouzova – Hristova)

16.30 – 17.30

• INFRAACT and the National Roadmap of Research Infrastructures – Cell technologies and innovations in biomedicine, Rossitza Konakchieva, Project manager, EATRIS ND
• INFRAACT R&TD capacity presentation of IBIR – BAS, Soren Hayrabedyan, Coordinator
• EATRIS – Bulgaria node snapshot 2023, Georgi Georgiev, EATRIS NC

17.30 – 18.30

• The LI-COR technology for reproducible in vitro, in vivo & ex vivo analyses, Nikolaos Parisis, PhD

Solutions & Support Scientist, Bio, Li-Cor, Germany

• Application of novel IR imaging approached to visualize inflammation at the level of cells, tissues, and organs, Rostyslav Bilyy, Ukraine
• From Bench to Bedside: Patient-Oriented Radiopharmaceutical Development in Nuclear Medicine Based on the Example of [89Zr]Zr-PSMA-DFO, Feodor Braun, Germany

• Pharma exhibition

Cocktail

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EATRIS-Bulgaria Annual Conference 2024

Scientific symposium “ADVANCES IN TRANSLATIONAL MEDICINE”

8 November 2024, Grand Hotel Sofia, Sofia, Bulgaria

09.00 – 9.30 Registration and welcome

09.30 – 13.00 Plenary session on Cell reprogramming, advanced technologies and experimental models

Key-note 09.30-09.50 Anna Veiga, Generation of human induced pluripotent stem cells from haplo-selected cord blood samples, CA21151, Barcelona, Spain

09.50-10.10 Manlio Vinciguerra, Integrative CUT&Tag-RNA-Seq Analysis: A Unified Workflow for Enhanced Insights Human Induced Pluripotent Stem Cell Reprogramming, TRANSTEM, MU-Varna

10.10-10.30 Ying Chen, Clinical Studies Database for hPSC-derived Cell Therapies, Fraunhofer IBMT, Germany

10.30-10.50 Dimiter Avtanski, Advances in Translational Medicine: The Impact of Adipose Tissue Stem Cells on Inflammation, Metabolic, and Cancer Pathways, Lenox Hill Hospital USA

10.50 – 11.10 Coffee break

11.10–11.30 Milena Murdjeva, Bioprinted Mesenchymal Stem Cells for critical bone defect regeneration, IBIR- BAS

11.30-11.50 Tsvetelina Oreshkova, Some highlights in modeling of endometrial maturation during pregnancy, IBIR-BAS

11.50-12.10 Mariastefania Antica, Regeneration of Immune Function through Thymic Epithelial Stem Cells, Ruđer Bošković Institute, Zagreb, Croatia

12.10 -12.30 Jordan Doumanov, Design of hBest-1 containing nanocomposites for drug delivery and treatment of bestrophinopathies, Sofia University

12.30-12.50 Mitko Mladenov, Dual Activation of Soluble Guanylate Cyclase Binding Sites: NO-Dependent and Independent Regulation of Stretch-Activated Channels in Rat Ventricular Cardiomyocytes, MU Skopje

12.50-13.10 P1lamen Zagorchev, Targeted/controlled release of bioactives – an experimental approach, MU-Plovdiv

13.00 – 14.00 Lunch break – Cocktail

14.00 – 18.00 – Plenary session – Translational genomics and biomarkers

Key note 14.00 – 14.40 Soren Hayrabedyan,Long-Read Nanopore Sequencing: Unlocking Novel Therapeutic Targets in Advanced Castration-Resistant Prostate Cancer, IBIR-BAS

14.40 – 15.00 Todor Popov, Global microRNA expression profile in laryngeal carcinoma unveils new prognostic biomarkers and novel insights into field cancerization – MU-Sofia

15.00 -15.20 Darina Kachakova, Comprehensive genetic studies in hereditary cancer syndromes, MU – Sofia

15.20 – 15.40 Russka Shumnalieva, CAR-T cell therapy in autoimmune rheumatic diseases, MU – Sofia

15.40 – 16.40 Junior Scientists Session – Short talks

Leonardo Martin, In Vivo and Ex Vivo Gene Therapy Strategies for Tissue Regeneration: Applications in Peripheral Arterial Disease and Muscle Contusion, University of Antwerp, Belgium

Anna Brymova, Human iPSC-derived RPE cells transplantation as a potential advanced medicinal therapy product for treatment of Age-related macular degeneration, Academy of Sciences of CR, Libechov, Czech Republic

Georgi Boyadzhiev, Analysis of extracellular vesicles in a model of human endometrial cell differentiation, IBIR-BAS

Andrey Velichkov, Transcriptome alterations contribute to immune evasion in the prostate cancer stem-like phenotype, IBIR- BAS

Antonina Gospodinova, Developing an Extensive Mitochondrial Damage Research Protocol Incorporating Adaptive Sampling and Fluorescence Imaging Techniques, IBIR-BAS

Petar Eftimov, MSC treatment in patient homozygous for the high-risk factor for DM in exon 2 of the SOD1-gene – a promising prospective case report, FB SU

16.40 – 18.00 Coffee break and on-line poster session

19.00-22.00 Welcome dinner at the City Center for Invited Speakers

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EATRIS-Bulgaria Annual Conference 2024

9 November 2024 Grand Hotel Sofia, Sofia, Bulgaria

09.30 – 10.00 Young researcher award session

10.00 – 12.00 Joint session of EATRIS-Bulgaria and BBMRI national nodes on: Biobanking and Translational Medicine – opportunities, challenges and perspectives

Radka Kaneva – Partnership in European-wide initiatives: EvolveBBMRI, ERDERA, GDI and Genome of Europe, BBMRI.bg NN

Georgi Georgiev – EATRIS Flagship Project EATRIS-Connect: concept and implementation, Sofia University, EATRIS-Bulgaria NN

Georgi Nikolov – Updates in European legislation on quality and safety standards for substances of human origin intended for human use, MC ReproBioMed

Plamen Todorov – Cryopreservation and biobanking of human stem cells in Bulgaria – an overview, IBIR-BAS

Rossitza Konakchieva – BG niche in the COST initiatives on iPSC biobanking, Sofia University, EATRIS-Bulgaria NN

12.00 Cocktail and networking

13.00 Closing